Cefepime-induced encephalopathy

Cefepime-induced encephalopathy

Accepted 3 January 2018 DesCripTion A 61-year-old man has been unable to leave his bed since being diagnosed with cerebral palsy at the age of 2 years. He is fed via a gastrostoma and has previously contracted aspiration pneumonitis three times. He has had no history of seizures or myoclonic movements until the time of hospitalisation. He visited a physician with complaints of fever lasting for...

Cefepime-induced encephalopathy with normal renal function

Cefepime is a fourth-generation cephalosporin that is frequently used in a wide array of infections. Since approval for use, concerns have been raised due to adverse effects including seizures, encephalopathy and myoclonus especially if renal dysfunction is present. Despite having appropriate renal dose adjustments, cases have been found with adverse neurological effects. On this occasion, we p...

Cefepime-Induced Encephalopathy, Single-Center Incidence, Complexities in Diagnosis

Cefepime-induced encephalopathy in patient without renal failure.

This case report describes neurotoxicity in an older patient on cefepime 2 g twice a day. The 81-year-old male patient developed non-convulsive status epilepticus during cefepime treatment with 1 g twice a day. There was recovery 30 days after discontinuation of cefepime.

Cefepime-induced encephalopathy with triphasic waves in three Asian patients.

Dear Editor, Cefasporins such as cefepime are beta-lactam antibiotics with a broad antimicrobial spectrum. They are commonly used as first-line agents in the treatment of many infections.1 Reversible encephalopathy is a known neurotoxic complication of cefalosporins.2 Previous case reports have documented triphasic waves on electroencephalography (EEG) in cephalosporin-induced encephalopathy.1-...